上海针灸杂志2023,Vol.42Issue(12):1288-1292,5.DOI:10.13460/j.issn.1005-0957.2023.12.1288
药线点灸联合针挑治疗坐骨神经痛的疗效观察及对相关炎症因子的影响
Observation of medicated thread moxibustion in combination with needle pricking in the treatment of sciatica and its influence on related inflammatory factors
摘要
Abstract
Objective To observe the clinical efficacy of medicated thread moxibustion combined with needle pricking in the treatment of sciatica and its effect on serum related inflammatory factors interleukin-6(IL-6),interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)levels.Method A total of 72 sciatica patients were randomly divided into a control group and a combination group,with 36 cases in each group.The patients in the combination group were treated with medicated thread moxibustion combined with needle pricking,and the patients in the control group were treated with oral indomethacin tablets and quick-acting sciatica pills.The clinical efficacy,pain visual analog scale(VAS)score,lumbar function score,and levels of IL-6,IL-1β and TNF-α were observed and compared between the two groups.The incidence of adverse reactions was compared between the two groups.Result The curative rate of the combination group was higher than that of the control group(P<0.05).Compared with the control group after treatment,the pain VAS score and lumbar spine function score were decreased after treatment in the combination group(P<0.05).After treatment,the serum levels of IL-6,IL-1β and TNF-α in the combination group were lower than those in the control group(P<0.05).The incidence of adverse reactions in the combination group was lower than that in the control group(P<0.05).Conclusion Medicated thread moxibustion combined with needle pricking can effectively relieve sciatica,and the curative effect is better than oral medication,which may be related to the regulation of inflammatory factors IL-6,IL-1β and TNF-α levels,and has fewer adverse reactions.关键词
灸法/药线/针刺疗法/挑治/神经痛/坐骨神经痛/疼痛/炎症因子Key words
Moxibustion/Medicated thread/Acupuncture therapy/Needle pricking/Neuralgia/Sciatica/Pain/Inflammatory factors分类
医药卫生引用本文复制引用
王谨莹,张旭清,唐汉庆,李克明,陆青兰..药线点灸联合针挑治疗坐骨神经痛的疗效观察及对相关炎症因子的影响[J].上海针灸杂志,2023,42(12):1288-1292,5.基金项目
国家自然科学基金项目(81960911) (81960911)