护理研究2023，Vol.37Issue(24)：4408-4412,5.DOI:10.12102/j.issn.1009-6493.2023.24.008
前列腺癌根治术后发生膀胱痉挛风险预测模型的构建与验证
Construction and validation of a risk prediction model for bladder spasm after radical prostatectomy
摘要
Abstract
Objective:To explore the risk factors of bladder spasm after radical prostatectomy in patients with prostate cancer,and to establish and verify the risk early warning model.Methods:From January 2020 to September 2021,120 patients undergoing radical prostatectomy in our hospital were selected.According to whether bladder spasm occurred after operation,they were divided into occurrence group(n=32)and non-occurrence group(n=88).Logistic regression analysis was performed on possible related factors,and a nomogram risk model was constructed and verified.Results:The incidence of bladder spasm after radical prostatectomy in 120 patients with prostate cancer was 26.67％.Age,BMI,preoperative IPSS score and catheter retention time were independent risk factors for bladder spasm after radical prostatectomy(P<0.05).Pelvic floor muscle training,preservation of prostate urethra and preservation of bladder neck were independent protective factors(P<0.05).The results of Hosmer-Lemeshow goodness of fit test showed that x2= 9.052,P=0.338;the area under the ROC curve was 0.981(P<0.001,95％CI 0.956-1.000),the sensitivity was 90.60％,the specificity was 97.70％,the maximum Youden index was 0.883,the overall trend of the model correction curve was close to the ideal curve,and the clinical application accuracy was 79.52％.The decision curve(DCA)analysis showed that the prediction model showed a positive net benefit when the threshold was 0.10-0.92.Conclusions:The occurrence of bladder spasm after radical prostatectomy in patients with prostate cancer is affected by multiple factors.The risk warning model established according to the factors has good predictive efficacy.关键词
前列腺癌/根治术/膀胱痉挛/风险预警模型/影响因素Key words
prostate cancer/radical surgery/bladder spasm/risk early warning model/influencing factor引用本文复制引用
廖晓红,吴金华,曾秋萍,何燕妃,汪林芳..前列腺癌根治术后发生膀胱痉挛风险预测模型的构建与验证[J].护理研究,2023,37(24):4408-4412,5.基金项目
江西省中医药管理局科技计划,编号:2022B620 （）
