外科理论与实践2023，Vol.28Issue(5)：448-453,6.DOI:10.16139/j.1007-9610.2023.05.10
双重滤过血浆置换对高脂血症性急性胰腺炎的疗效分析
Analysis of the effect of double filtration plasmapheresis on hyperlipidemic acute pancreatitis
葛焱 1王国鑫 1王佳卉 1安源 1赵冰 1盛慧球 1马丽1
作者信息
- 1. 上海交通大学医学院附属瑞金医院急诊科,上海 200025
- 折叠
摘要
Abstract
Objective To evaluate the effect of double filtration plasmapheresis(DFPP)on patients with hyperlipidemic acute pancreatitis(HL-AP).Methods The clinical data of the patients with hyperlipidemic severe acute pancreatitis(HL-SAP)or moderately severe acute pancreatitis(HL-MSAP)from January 2019 to May 2022 were collected.The patients were divided into two groups,the control group received conventional treatment,DFPP group received DFPP treatment on the basis of conventional treatment.Results Compared with the control group,the following parameters changed significantly in DFPP group,triglyceride(TG),alanine aminotransferase(ALT)and aspartate aminotransferase(AST)decreased on day 1 and 2,estimated glomerular filtration rate(eGFR)increased on day 1,2,3 and 5,leukocyte and neutrophil counts decreased on day 1 and 2,hemoglobin(HGB)decreased on day 1,2,and 3,C-reactive protein(CRP)decreased on day 1,2,3,5,and 7.And the patients in DFPP group receiving mechanical ventilation decreased compared with that in control group.Conclusion Compared with conventional treatment,DFPP can reduce plasma TG faster,improve lung,liver and kidney function,reduce inflammatory markers,and facilitate early fluid recovery.关键词
高脂血症性急性胰腺炎/双重滤过血浆置换/多器官功能障碍综合征Key words
Hyperlipidemic acute pancreatitis/Double filtration plasmapheresis/Multiple organ dysfunction syndrome分类
医药卫生引用本文复制引用
葛焱,王国鑫,王佳卉,安源,赵冰,盛慧球,马丽..双重滤过血浆置换对高脂血症性急性胰腺炎的疗效分析[J].外科理论与实践,2023,28(5):448-453,6.
