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PG1/PG2与肿瘤标志物预测中晚期胃癌近期生存

盛超 王俊先 黄家惠 刘冬 徐娟 李绍雪

现代科学仪器2023,Vol.40Issue(6):53-57,5.
现代科学仪器2023,Vol.40Issue(6):53-57,5.

PG1/PG2与肿瘤标志物预测中晚期胃癌近期生存

Prediction of PG1/PG2 and tumor markers on short-term survival in advanced gastric cancer

盛超 1王俊先 2黄家惠 2刘冬 1徐娟 1李绍雪1

作者信息

  • 1. 安徽医科大学合肥第三临床学院(合肥市第三人民医院)
  • 2. 安徽省第二人民医院
  • 折叠

摘要

Abstract

Objective:To analyze the value of analyzing serum PG1/PG2,CEA,and CA125 in predicting short-term survival of advanced gastric cancer.Methods:110 patients with advanced gastric cancer and 110 healthy volunteers were selected.Serum PG1,PG2,CEA,CA125 were detected,and the patients were followed up for 1 year.Results:Serum PG1/PG2 in the cancer group was lower(P<0.05),while CEA and CA125 levels were higher(P<0.05),all of which were related to gastric cancer stage,pathological types and recent survival(P<0.05).The combined prediction of serum PG1/PG2,CEA and CA125 had a higher AUC(P<0.05).Conclusion:The decrease of serum PG1/PG2 and the increase of CEA and CA125 in advanced gastric cancer are related to clinical pathological characteristics,and the combined prediction of short-term survival has high value.

关键词

胃蛋白酶原1/胃蛋白酶原2/癌胚抗原/糖类抗原125/胃癌/生存

Key words

Pepsinogen 1/Pepsinogen 2/Carcinoembryonic antigen/Carbohydrate antigen 125/Gastric cancer/Survival

分类

医药卫生

引用本文复制引用

盛超,王俊先,黄家惠,刘冬,徐娟,李绍雪..PG1/PG2与肿瘤标志物预测中晚期胃癌近期生存[J].现代科学仪器,2023,40(6):53-57,5.

基金项目

2021年度安徽省卫生健康委科研项目AHWJ2021b094 ()

现代科学仪器

1003-8892

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