畜牧兽医学报2023，Vol.54Issue(12)：4910-4919,10.DOI:10.11843/j.issn.0366-6964.2023.12.003
肠道菌群抗病毒机制研究进展
Research Progress in Antiviral Mechanism of Intestinal Microflora
摘要
Abstract
In recent years,with the deepening research on the intestinal microbiota and a clearer understanding of its relationship with organismal health,it has been found that the intestinal mi-crobiota plays a dual role in regulating viral infections.The intestinal microbiota can inhibit viral infection by protecting the intestinal mucosal barrier,directly neutralizing viruses or preventing their effects on cell adhesion,indirectly influencing the establishment and development of the body's immune system,and secreting antiviral metabolites to play an antiviral role.Moreover,probiotics have played an increasingly prominent role in disease treatment,and it is expected that probiotics can overcome the disadvantages of current viral disease treatments.This paper reviews the research progress on the mechanisms of the intestinal microbiota's resistance to viral infection in recent years and discusses related issues and future directions for research.关键词
肠道菌群/抗病毒机制/黏膜屏障/免疫调节/菌群代谢物Key words
intestinal microflora/antivirus mechanism/mucosal barrier/immunomodulation/microbial metabolites分类
农业科技引用本文复制引用
宫浩阳,唐丽杰,吴佳鑫,杨晓钰,解伟纯,王雪莹,李佳璇,姜艳平,崔文,李一经..肠道菌群抗病毒机制研究进展[J].畜牧兽医学报,2023,54(12):4910-4919,10.基金项目
国家自然科学基金联合基金项目(U22A20527) （U22A20527）
