畜牧兽医学报2023，Vol.54Issue(12)：4920-4933,14.DOI:10.11843/j.issn.0366-6964.2023.12.004
猪链球菌耐药现状分析及感染防控措施
Drug Resistance Situation of Streptococcus suis and Prevention Measures of Infections
摘要
Abstract
Streptococcus suis(S.suis)infection has long plagued the health and sustainable development of our pig industry.In particular,the emergence of drug-resistant strains will block the original prevention and control strategy of streptococcosis.The summary of the prevalence of resistance to S.suis at China and abroad in recent years can provide effective measures for the prevention and treatment of S.suis infection.Therefore,we first summarized the S.suis infec-tion situation in large-scale pig farms at home and abroad in the past five years(most positive rate＞40％).Among them,the serotype 2 strain is the most widespread in all provinces and cit-ies in China.Subsequently,we summarized the epidemic status and infection characteristics of drug-resistant S.suis in pig farms,and found that drug-resistant S.suis in large-scale pig farms concentrated in the Asian and Europe,and the drug resistance exceeded 80％in the most regions,mainly tetracycline resistant strains.However,resistance to S.suis in large-scale pig farms in our country is mainly tetracycline and macrolide resistance.In addition,S.suis is a zoonotic a-gent that can cause systemic infection through the respiratory tract and blood.Finally,in view of the characteristics of S.suis strain variation,we proposed the importance of accurate detection for the prevention and control of S.suis,summarized the rapid detection methods.The preven-tion and control measures based on vaccination,combined drug use and the development of new host-directed antibiotics are emphasized to provide data support for the subsequent prevention and control of resistant strains of S.suis.关键词
猪链球菌/耐药性现状/防治措施Key words
Streptococcus suis/drug resistance/prevention and control measures分类
农业科技引用本文复制引用
吕若一,司晓慧,孙志刚,史晓敏,刘晓晔..猪链球菌耐药现状分析及感染防控措施[J].畜牧兽医学报,2023,54(12):4920-4933,14.基金项目
北京市自然科学基金资助项目(6224060) （6224060）
北京农学院青年教师科研创新能力提升计划(QJKC2022028) （QJKC2022028）
北京农学院科技创新"火花行动"支持计划(BUA-HHXD2022007) （BUA-HHXD2022007）
