畜牧兽医学报2023,Vol.54Issue(12):5293-5300,8.DOI:10.11843/j.issn.0366-6964.2023.12.037
肉鸽肠道微生物菌群差异分析和抗生素耐药基因预测
Differential Analysis and the Antibiotic Resistance Genes Prediction of Gut Microbiota in Pigeon
摘要
Abstract
In this study,metagenomics was used to explore the fecal microbiota differences be-tween the young pigeons(RP)and older pigeons(LP).The results showed that Firmicutes,Proteobacteria and Actinobacteria were the dominant bacterias.The contents of Bifidobacteri-um,Corynebacteriun,Psychrobacter and Streptococcus in RP group were significantly higher than those in LP group,while the relative abundance of Staphyloccus,Brachybacterium,Kurthia and Escherichia in LP group were significantly higher than those in RP group.Further LEfSe analysis showed that the differentially expressed genes in the two groups were enriched in 5 KEGG pathways.Antibiotic resistance genes(ARGs)analyzation showed that a total of 198 ARG,were identified.And the prevalence rate of multi-drug ARGs was more than 40%,which indicated that the antibiotic resistance problem in pigeon is seriously.The current study provided scientific datas for further researches on gut microflora and healthy breeding,and mechanism of antibiotic resistance mechanism.关键词
肉鸽/宏基因组学/肠道菌群/抗生素耐药基因Key words
pigeon/metagenomics/gut microbiota/antibiotic resistance gene分类
农业科技引用本文复制引用
陶洁,李本强,程靖华,石迎,刘佩红,刘惠莉..肉鸽肠道微生物菌群差异分析和抗生素耐药基因预测[J].畜牧兽医学报,2023,54(12):5293-5300,8.基金项目
上海市肉鸽产业技术体系(沪农科产字(2022)第12号) (沪农科产字(2022)
动物疾病防控团队(沪农科卓[2022]012) (沪农科卓[2022]012)