新医学2023，Vol.54Issue(12)：855-859,5.DOI:10.3969/j.issn.0253-9802.2023.12.003
TEM8在恶性肿瘤中的研究进展
Research progress on TEM8 in malignant tumors
摘要
Abstract
Tumor endothelial marker 8(TEM8)is a highly-conserved single-shot transmembrane glycoprotein.TEM8 is a special member of the tumor endothelial marker family,which was first discovered in colon cancer tissues.Studies have shown that TEM8 is specifically expressed in a variety of malignant tumor cells and tumor vascular endothelia,and participates in malignant biological behaviors,such as tumor proliferation and angiogenesis,which is a biomarker for early diagnosis and prognosis of some malignant tumors,and can be used as a new target for the treatment of malignant tumors.This article will introduce the mechanism of TEM8 in malignant tumors and its clinical application progress.关键词
肿瘤内皮细胞标志物8/恶性肿瘤/靶点/机制通路Key words
Tumor endothelial marker 8/Malignant tumor/Target/Mechanism pathway引用本文复制引用
黄芙蓉,冯诚天,曹世玉,姜永冬..TEM8在恶性肿瘤中的研究进展[J].新医学,2023,54(12):855-859,5.基金项目
黑龙江省博士后科研基金(LBH-Q20133) （LBH-Q20133）
