疑难病杂志2023,Vol.22Issue(12):1340-1344,5.DOI:10.3969/j.issn.1671-6450.2023.12.022
骨髓间充质干细胞通过调节免疫及炎性反应治疗膝骨性关节炎机制的研究进展
Bone marrow mesenchymal stem cells in immune and inflammatory modulation of osteoarthritis of the knee
摘要
Abstract
The development of osteoarthritis(OA)is not simply a result of cartilage damage and alteration of the a-lignment of forces,but the immune aspect also has a huge impact on OA,and BMSCs(bone marrow mesenchymal stem cells),as a kind of cells with multi-directional differentiation ability,have great potential in the role of immune regulation and tissue regeneration,and studies have shown that the pathogenesis of OA is closely related to This paper is a review of the biological properties,mechanisms of action,problems and prospects of BMSCs.关键词
骨性关节炎/骨髓间充质干细胞/免疫反应/炎性反应Key words
Osteoarthritis/Bone marrow mesenchymal stem cells/Immune response/Inflammatory response分类
医药卫生引用本文复制引用
张文豪,向文远,方锐..骨髓间充质干细胞通过调节免疫及炎性反应治疗膝骨性关节炎机制的研究进展[J].疑难病杂志,2023,22(12):1340-1344,5.基金项目
新疆维吾尔自治区科研领军项目(2022TSYCLJ0007) (2022TSYCLJ0007)
新疆维吾尔自治区自然科学基金重点项目(2021B03006) (2021B03006)
新疆维吾尔自治区自然科学基金(2022D01C170)Xinjiang Uygur Autonomous Region Scientific Research Leadership Program(2022TSYCLJ0007) (2022D01C170)
Key Project of Natural Science Foundation of Xinjiang Uygur Autonomous Region(2021B03006) (2021B03006)
Natural Science Foundation of Xinjiang Uygur Autonomous Region(2022D01C170) (2022D01C170)