摘要
Abstract
Objective To study the clinical significance of β-human chorionic gonadotropin(β-hCG)and progesterone(P)in the diagnosis of early pregnancy,early tubal ectopic pregnancy and early threatened abortion.Methods The clinical data of early pregnancy(23 patients),early tubal ectopic pregnancy(40 patients)and early threatened abortion(39 patients)diagnosed and treated in our hospital from January to December 2022 were retrospectively analyzed.The levels of serum β-hCG and P in different patients were compared.The diagnostic efficacy(accuracy,sensitivity,specificity)of serum β-hCG and P alone and combined detection of serum β-hCG and P in early tubal ectopic pregnancy and early threatened abortion,while serum β-hCG and P levels in early threatened abortion patients with different pregnancy outcomes were analyzed.Results The levels of serum β-hCG and P in early pregnancy were higher than those in early tubal ectopic pregnancy and early threatened abortion,and the levels of serum β-hCG and P in early threatened abortion were higher than those in early tubal ectopic pregnancy(P＜0.05).The accuracy,sensitivity and specificity of combined detection of serum β-hCG and P in the diagnosis of early tubal ectopic pregnancy and early threatened abortion were higher than those of serum β-hCG and P alone(P＜0.05).There was no significant difference in the sensitivity and accuracy of serum β-hCG detection and Pdetection in the diagnosis of early tubal pregnancy(P＞0.05).The specificity of serum β-hCG detection in the diagnosis of early tubal ectopic pregnancy was lower than that of P detection(P＜0.05).There was no significant difference in the sensitivity,specificity and accuracy of serum β-hCG detection and P detection in the diagnosis of early threatened abortion(P＞0.05).The levels of serum β-hCG and P in patients with spontaneous abortion were lower than those in patients with continuous pregnancy(P＜0.05).Conclusion Serum β-hCG and progesterone play an important role in the diagnosis of early pregnancy,early tubal ectopic pregnancy and early threatened abortion,and can be used as differential diagnostic indicators.In particular,the combined detection of serum β-hCG and P can improve the accuracy and sensitivity of early tubal ectopic pregnancy and threatened abortion,and can be used as a predictor of pregnancy outcome in patients with early threatened abortion,so as to provide a reliable reference for clinicians to effectively intervene.关键词
β-hCG/孕酮/早孕/早期输卵管妊娠/早期先兆流产Key words
β-hCG/Progesterone/Early pregnancy/Early tubal ectopic pregnancy/Early threatened abortion分类
临床医学
