医药导报2023，Vol.42Issue(12)：1900-1908,后插1,10.DOI:10.3870/j.issn.1004-0781.2023.12.028
基于数字化药学模式比较降压类带量采购药品与原研药品
Comparison of Volume-based Procurement and Innovator Antihypertensive Drugs Based on Digital Pharmaceutical Model
摘要
Abstract
Objective To comprehensively assess the strengths and weaknesses of the 24 antihypertensive drugs procured as Volume-based Procurement(VBP)and innovator drugs by using quantitative evaluation system,and to provide a reference for doctors and patients in medication guidance and pharmaceutical decision-making.Methods The Quantitative Evaluation Criteria in the"Quick Guide to Drug Evaluation and Selection in Chinese Medical Institutions"were refined and optimized.The 24 selected VBP and innovator antihypertensive drugs were quantitatively evaluated according to the optimized quantitative evaluation system with the help of Chinese and English databases such as China Knowledge Network,Wanfang data,Wipunet,Embased,PubMed,and Metstr,as well as guideline search tools such as Meikang MCDEX,Drugwise Data,Up To Date,Medical Pulse and other databases etc.Results Among the 24 antihypertensive drugs,only four innovator drug evaluation scores were higher than those of drugs selected as VBP,namely felodipine tablets,Fosinopril sodium tablets,indapamide extended-release capsules,Irbesartan hydrochlorothiazide tablets.there were five main differences in the evaluation scores,namely economy,consistency evaluation,drug expiry date,global use,and the status of manufacturing enterprises.It was found that 83%of the VBP drugs had higher evaluation scores than those of the innovator drugs.The economic score of the innovator drug was low,and the difference in the scores was between 1-11 points.Conclusion By using the quantitative evaluation system to evaluate the antihypertensive drugs,the advantages and disadvantages of the innovator and VBP antihypertensive drugs can be assessed comprehensively,and the digital characteristics of antihypertensive drugs can be given,and the evaluation score can provide the reference basis for the guidance and decision-making of medication for doctors and patients.关键词
药品评价/量化评价体系/带量采购/原研药品/数字化药学Key words
Drug evaluation/Quantitative evaluation system/Volume-based Procurement/Innovator drugs/Digital pharmacy分类
医药卫生引用本文复制引用
李宵,曹格溪,任炳楠,赵越,董占军..基于数字化药学模式比较降压类带量采购药品与原研药品[J].医药导报,2023,42(12):1900-1908,后插1,10.基金项目
白求恩·医学科学研究基金资助项目(N089NH) （N089NH）
