中国病理生理杂志2023，Vol.39Issue(12)：2259-2264,6.DOI:10.3969/j.issn.1000-4718.2023.12.017
结节病样肉芽肿动物模型的研究进展
Research progress in animal models of sarcoidosis
摘要
Abstract
Sarcoidosis is a systemic disease of unknown etiology characterized by the formation of noncaseating granulomas.Its clinical manifestations are heterogeneous,and the determinants of clinical course(such as active vs inac-tive,remission vs chronic progression,and fibrosis vs non-fibrosis)are poorly understood.Despite considerable effort over many years,the exact pathogenesis of sarcoidosis has not been fully elucidated.Animal models have made significant con-tributions to understanding the etiology and the development of this disease.In this review,we presented the clinical rele-vance of animal models in sarcoidosis,summarized the methods for constructing the models,and discussed how they have strengthened our understanding of sarcoidosis.关键词
结节病/动物模型/发病机制Key words
sarcoidosis/animal model/pathogenesis分类
医药卫生引用本文复制引用
韩悦殷,刘梦远,代华平,王辰..结节病样肉芽肿动物模型的研究进展[J].中国病理生理杂志,2023,39(12):2259-2264,6.基金项目
国家自然科学基金资助项目(No.92068108) （No.92068108）
