中国感染控制杂志2023，Vol.22Issue(12)：1493-1498,6.DOI:10.12138/j.issn.1671-9638.20234082
咽拭子联合肛拭子作为ICU多重耐药菌入院筛查的有效性评估
Effectiveness evaluation of pharyngeal swabs combined with anal swabs as multidrug-resistant organisms admission screening in intensive care unit
摘要
Abstract
Objective To evaluate the effectiveness of pharyngeal swabs combined with anal swabs as multidrug-resistant organism(MDRO)admission screening for patients in intensive care unit(ICU),and provide reference for healthcare-associated infection(HAI)prevention and control strategies.Methods Patients who underwent MDRO admission screening by pharyngeal swabs combined with anal swabs within 24 hours of admission to an ICU of a hospital in Shanghai from August 1 to December 31,2022 were included as the experimental group,and those who underwent MDRO admission screening only by pharyngeal swabs from August 1 to December 31,2021 were as the control group.Positive rate of screening,occurrence and pathogen of HAI between the two groups,as well as the sensitivity and specificity of combined admission screening for MDRO in the experimental group were compared.Results A total of 917 patients were included in the study,with 442 cases in the experimental group and 475 cases in the control group.The positive rates of admission screening for MDRO in the experimental and control groups were 7.40％and 3.37％,respectively.The incidences of HAI with MDRO in the experimental and control groups were 2.71％and 5.68％,respectively.Incidences of digestive system HAI with MDRO in the experimental and control groups were 0.68％and 2.32％,respectively.Differences were all statistically significant(all P＜0.05).The area under the ROC curve of admission screening by pharyngeal swabs combined with anal swabs for predicting HAI with MDRO in patients were 0.897(P＜0.01,95％CI:0.802-0.993).The sensitivity and specificity of admi-ssion screening for MDRO by pharyngeal swabs combined with anal swabs in the experimental group were 72.73％and 97.65％,respectively.Conclusion The combination of pharyngeal swabs and anal swabs can be used as an ICU admission screening method for MDRO,and has an important clinical application value.关键词
入院筛查/咽拭子/肛拭子/多重耐药菌/MRSA/CRE/医院感染Key words
admission screening/pharyngeal swab/anal swab/multidrug-resistant organism/MRSA/CRE/healthcare-associated infection分类
医药卫生引用本文复制引用
江一帆,费凯红,邹妮,庄燕萍,胡慧宇..咽拭子联合肛拭子作为ICU多重耐药菌入院筛查的有效性评估[J].中国感染控制杂志,2023,22(12):1493-1498,6.基金项目
上海市松江区科技攻关项目(20SJKJGG326) （20SJKJGG326）
上海市第一人民医院医院感染管理项目(SYYG20221040) （SYYG20221040）
