中国感染控制杂志2023,Vol.22Issue(12):1499-1505,7.DOI:10.12138/j.issn.1671-9638.20234730
2017-2021年某医院老年社区获得性血流感染患者临床特征及预后影响因素
Clinical characteristics and prognostic factors of elderly patients with CA-BSI in a hospital from 2017 to 2021
摘要
Abstract
Objective To explore the clinical characteristics and prognostic factors of elderly patients with commu-nity-acquired bloodstream infection(CA-BSI),and provide basis for clinical treatment and prevention.Methods Medical records of elderly patients diagnosed with CA-BSI in a tertiary first-class hospital of Changsha from 2017 to 2021 were collected.Patients were divided into a survival group and a death group according to the prognosis after 30 days hospitalization.The differences in clinical data between two groups of patients were compared,and influen-cing factors for the prognosis in CA-BSI patients were analyzed.Results A total of 575 elderly CA-BSI patients were included in the analysis,with 535 cases in the survival group and 40 cases in the death group.Univariate ana-lysis results suggested that death of elderly CA-BSI patients was related to gender,age,history of hemodialysis,glucocorticoid usage,indwelling catheter,concomitant heart disease,albumin,creatinine,and sequential organ fai-lure assessment(SOFA)score(all P<0.05).Multivariate logistic regression analysis results suggested that old age(OR=1.062,95%CI:1.016-1.109),high SOFA score(OR=1.161,95%CI:1.067-1.262),glucocorti-coid usage(OR=6.006,95%CI:2.441-14.774)were independent risk factors for the death of elderly CA-BSI patients,while normal albumin(OR=0.942,95%CI:0.891-0.995)was a protective factor.Conclusion Elderly CA-BSI patients have high risks of death.It is necessary to improve the immunity of patients as well as use antimi-crobial agents and glucocorticoids rationally,so as to reduce the risk of death in patients.关键词
老年/社区获得性血流感染/危险因素/预后Key words
elderly/community-acquired bloodstream infection/risk factor/prognosis分类
预防医学引用本文复制引用
阳赣萍,龙智勇,李林奇,陈湘香,谢和宾..2017-2021年某医院老年社区获得性血流感染患者临床特征及预后影响因素[J].中国感染控制杂志,2023,22(12):1499-1505,7.基金项目
湖南省自然科学基金项目(2020JJ8044) (2020JJ8044)
湖南省卫健委科研计划项目(20201936) (20201936)
长沙市科技计划项目(kq2004169) (kq2004169)