中国口腔种植学杂志2023，Vol.28Issue(6)：451-459,9.DOI:10.12337/zgkqzzxzz.2023.12.010
聚四氟乙烯膜改性个性化钛网的制备及其抗菌性能研究
Study on the preparation and antibacterial properties of polytetrafluoroethylene film modified customized titanium mesh
杨波 1韩泽奎 1代浩然 1张亮 1臧旖欣 1王心彧 1宿玉成2
作者信息
- 1. 黑龙江省生物医学材料及临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学口腔医学院 154002
- 2. 黑龙江省生物医学材料及临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学口腔医学院 154002||北京瑞城口腔医院 北京口腔种植培训中心(BITC) 100032||中国医学科学院北京协和医院口腔种植中心 100032
- 折叠
摘要
Abstract
Objective By preparing polytetrafluoroethylene film on the surface of customized titanium mesh,the biocompatibility and antibacterial ability of the surface of customized titanium mesh were improved.Methods The surface of the customized titanium mesh was sandblasted to roughen the surface by alumina and air-sprayed with PTFE dispersion.The polytetrafluoroethylene film modified customized titanium mesh(PMTM)was obtained by sintering and heat curing.The experimental groups were selective laser melting printing untreated group(CON),mechanical polishing group(MP),low-grit sandblasting group(SB),titanium-reinforced dense polytetrafluoroethylene film group(TRDP).The surface morphology,roughness,hydrophilicity,functional groups and phase composition of the samples were analyzed.The number and morphology of bacteria adhering to the surface of each group of samples after co-culture with Staphylococcus aureus and Escherichia coli were analyzed to evaluate the in vitro antibacterial ability of polytetrafluoroethylene film modified customized titanium mesh.Results The polytetrafluoroethylene film with stable bonding and a high purity is formed on the surface of the PMTM group,which reduced the micron-scale roughness and is highly hydrophobic.The number of bacteria on the surface of the CON group was the largest(P<0.001),and the numbers of bacteria on the surface of the MP and SB groups were lower.The PMTM and TRDP groups had the lowest bacterial adhesion,and their antibacterial adhesion effects were similar(P>0.05).Conclusion The preparation of polytetrafluoroethylene film on the surface of customized titanium mesh can improve its ability to inhibit bacterial adhesion,which is an ideal surface treatment method for customized titanium mesh.关键词
个性化钛网/聚四氟乙烯/引导骨再生/表面处理/抗菌性能Key words
Customized titanium mesh/Polytetrafluoroethylene/Guided bone regeneration/Surface treatment/Antibacterial properties引用本文复制引用
杨波,韩泽奎,代浩然,张亮,臧旖欣,王心彧,宿玉成..聚四氟乙烯膜改性个性化钛网的制备及其抗菌性能研究[J].中国口腔种植学杂志,2023,28(6):451-459,9.
