中国临床医学2023，Vol.30Issue(6)：927-933,7.DOI:10.12025/j.issn.1008-6358.2023.20221557
超声心动图评价房间隔缺损合并肺动脉高压患者接受介入封堵术前后左心室纵向收缩功能
Echocardiographic evaluation of left ventricular longitudinal systolic function in patients with atrial septal defect and pulmonary hypertension before and after interventional occlusion
摘要
Abstract
Objective To investigate the dynamic changes of left ventricular longitudinal systolic function in patients with atrial septal defect(ASD)and pulmonary hypertension(PH)before and after interventional occlusion using echocardiography.Methods A total of 57 patients undergoing interventional occlusion in Zhongshan Hospital,Fudan University from September 2015 to January 2016 were enrolled.Patients were divided into PH group and non-PH group.Echocardiographic examinations were performed for all subjects one day before,one day after and 1-6 months after the interventional occlusion.Twenty healthy individuals were included as a control group.Global and regional longitudinal strain(LS)of the left ventricle were analyzed using TomTec software.Results There were 27 patients in the PH group and 30 patients in the non-PH group.At baseline,tricuspid annular plane systolic excursion(TAPSE)and tissue Doppler velocity of tricuspid annulus S'in both the PH and non-PH groups were higher than those in the control group(P＜0.05).Longitudinal systolic function of the right ventricle decreased significantly on the first day after occlusion(P＜0.05),and slightly increased 1-6 months after occlusion.Patients in the non-PH group showed a decreased LS in a small portion of the left ventricular segments 1 d and 1-6 months after occlusion(P＜0.05);patients in the PH group showed a decreased left ventricular global longitudinal strain(GLS)on the first day after occlusion(P＜0.05),primarily was in the basal and middle parts of the ventricle(P＜0.05),without significant change in the apical part,and the LS of the left ventricle tended to increase 1-6 months after occlusion.Conclusions With or without PH,longitudinal movement of the right ventricle in ASD patient is excessive before occlusion,and gradually improves after occlusion.Left ventricular GLS decreases in ASD patients with PH,with segmental differences 1 day after occlusion.关键词
超声心动图/心室功能/三维纵向应变/房间隔缺损/肺动脉高压Key words
echocardiography/left ventricular function/three-dimensional longitudinal strain/atrial septal defect/pulmonary hypertension分类
医药卫生引用本文复制引用
左武旭,吴元丰,李权,陈丹丹,董丽莉,孔德红,潘翠珍,舒先红..超声心动图评价房间隔缺损合并肺动脉高压患者接受介入封堵术前后左心室纵向收缩功能[J].中国临床医学,2023,30(6):927-933,7.基金项目
国家自然科学基金(81771837),上海市卫生健康委员会青年基金项目(20204Y0345),上海申康临床研究青年项目(SHDC2020CR4071).Supported by National Natural Science Foundation of China(81771837),Youth Foundation of Shanghai Municipal Health Commission(20204Y0345)and Clinical Research Plan of SHDC(SHDC2020CR4071). （81771837）
