中国临床医学2023，Vol.30Issue(6)：988-992,5.DOI:10.12025/j.issn.1008-6358.2023.20231393
主动脉根部缺如的房间隔缺损经导管介入治疗疗效分析
Transcatheter closure of atrial septal defect with complete aortic rim deficiency
摘要
Abstract
Objective To investigate the safety and efficacy of interventional therapy in patients with secondary atrial septal defect(ASD)with complete aortic rim deficiency.Methods 402 patients with ASD who underwent transcatheter closure and followed up in outpatient at both 6-month and 1-year in the Department of Cardiology,Zhongshan Hospital,Fudan University from January 2018 to June 2020 were enrolled.They were divided into complete aortic rim deficiency group and normal aortic rim group.The clinical features,interventional parameters,and complications were compared between the two groups.Echocardiographic were used to evaluate the outcome.Results The occluder size was larger in the aortic rim deficiency group([26.4±6.9]mm,n=128)than that in normal aortic rim group([23.4±7.7]mm,P＜0.001;n=274).Both groups exhibited no major postoperative complications,and significant improvements were observed in right heart remodeling following the operation,including pulmonary artery pressure decreasing,the diameters of the right atrium and right ventricle reducing,and the degree of tricuspid regurgitation reducing(P＜0.001).There was no significant change in left ventricular ejection fraction in all patients.Conclusion Transcatheter closure of ASD with complete aortic rim deficiency is safe and feasible.关键词
主动脉根部缺如/房间隔缺损/介入治疗/安全性Key words
aortic rim deficiency/atrial septal defect/transcatheter therapy/safety分类
医药卫生引用本文复制引用
李明飞,林大卫,潘文志,张晓春,陈莎莎,张蕾,周达新,葛均波..主动脉根部缺如的房间隔缺损经导管介入治疗疗效分析[J].中国临床医学,2023,30(6):988-992,5.基金项目
上海市科学技术委员会基金(21S31904500).Supported by Fund of Shanghai Municipal Commission of Science and Technology(21S31904500). （21S31904500）
