中国免疫学杂志2023,Vol.39Issue(12):2638-2645,8.DOI:10.3969/j.issn.1000-484X.2023.12.031
小肠固有免疫与糖尿病的研究进展
Research progress of intestinal innate immunity and diabetes mellitus
摘要
Abstract
Diabetes mellitus(DM),as a common and frequently-occurring disease,has become a huge burden of chronic diseases worldwide,whose pathogenesis is very complex and has not yet been fully elucidated.Small intestine is one of important immune organ in body,and relationship between its innate immune function and DM has become forefront of research in medical field.In this paper,role of intestinal innate immunity in pathogenesis of DM is reviewed,including tissue barrier dysfunction of small intestine,dysfunction of intestinal innate immune cells and imbalance of proportion of intestinal innate immune molecules,in order to provide references for future research on related mechanisms.关键词
糖尿病/小肠/固有免疫Key words
Diabetes mellitus/Intestinal/Innate immune分类
医药卫生引用本文复制引用
周琳悦,刘雪辉,刘燕,贾华楠,马旭红,谢春光..小肠固有免疫与糖尿病的研究进展[J].中国免疫学杂志,2023,39(12):2638-2645,8.基金项目
本文受国家自然科学基金(81904082) (81904082)
四川省科技厅重点研发项目(2019YFS0022)资助. (2019YFS0022)