中国免疫学杂志2023，Vol.39Issue(12)：2646-2655,10.DOI:10.3969/j.issn.1000-484X.2023.12.032
革兰氏阳性菌细胞外囊泡研究进展
Research progress on extracellular vesicles of Gram-positive bacteria
摘要
Abstract
Extracellular vesicles(EVs)are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells.EVs se-creted by Gram-negative bacteria have been extensively studied for many years,but due to differences in cell wall structure,EVs in Gram-positive bacteria have been disregarded.However,the production of EVs in Gram-positive bacteria was confirmed in recent stud-ies.Components of EVs are diverse,including proteins,lipids,nucleic acids and metabolites,play important role in biofilm forma-tion,antibiotic resistance,horizontal gene transfer(HGT)and pathogenesis.EVs have potential applications and are involved in the fields of vaccine research and development,disease treatment and drug delivery.Here,we review the latest findings on the biogene-sis,components,applications and functions of EVs from Gram-positive bacteria,hoping to provide a reference for the research in the field of EVs in Gram-positive bacteria.关键词
革兰氏阳性菌/细胞外囊泡/功能/应用Key words
Gram-positive bacteria/Extracellular vesicles/Functions/Applications分类
生物学引用本文复制引用
徐兆坤,李敏,罗海霞..革兰氏阳性菌细胞外囊泡研究进展[J].中国免疫学杂志,2023,39(12):2646-2655,10.基金项目
本文受国家自然科学基金(31960694,31760035) （31960694,31760035）
宁夏回族自治区自然科学基金(2021AAC05008)资助. （2021AAC05008）
