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lncRNAs在系统性红斑狼疮中的研究进展

尚双双 李明 黄传兵

中国免疫学杂志2023,Vol.39Issue(12):2662-2665,2671,5.
中国免疫学杂志2023,Vol.39Issue(12):2662-2665,2671,5.DOI:10.3969/j.issn.1000-484X.2023.12.034

lncRNAs在系统性红斑狼疮中的研究进展

Research progress of lncRNAs in systemic lupus erythematosus

尚双双 1李明 2黄传兵2

作者信息

  • 1. 安徽中医药大学,合肥 230038
  • 2. 安徽中医药大学第一附属医院风湿科,合肥 230031
  • 折叠

摘要

Abstract

Long non-coding RNAs(lncRNAs)can be involved in regulating gene expression through multiple interactions with DNA,RNA or proteins.Studies have shown that lncRNAs not only regulate innate immune response,but also regulate immune cell development and adaptive immunity.According to recent reports,a number of lncRNAs play a role in the pathogenesis of immune-mediated inflammatory diseases,including systemic lupus erythematosus(SLE),and may become a diagnostic marker and prognostic reference for diseases.This paper summarizes the research progress of lncRNAs in SLE,with the hope of providing more new ideas and methods for the study of SLE.

关键词

lncRNAs/系统性红斑狼疮/发病机制/生物标志物

Key words

LncRNAs/Systemic lupus erythematosus/Pathogenesis/Biomarker

分类

临床医学

引用本文复制引用

尚双双,李明,黄传兵..lncRNAs在系统性红斑狼疮中的研究进展[J].中国免疫学杂志,2023,39(12):2662-2665,2671,5.

基金项目

本文为国家自然科学基金项目(81473672) (81473672)

安徽省高校自然科学研究项目(KJ2020A0395). (KJ2020A0395)

中国免疫学杂志

OACSCDCSTPCD

1000-484X

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