中国内镜杂志2023，Vol.29Issue(12)：20-25,6.DOI:10.12235/E20230111
硬质支气管镜术中应用罗库溴铵行深度肌松对喷射通气氧合效果的影响
Effect of deep muscle relaxation by rocuronium on oxygenation of jet ventilation during rigid bronchoscopy procedures
摘要
Abstract
Objective To observe the effect of deep muscle relaxation by rocuronium on oxygenation of normal frequency jet ventilation during rigid bronchoscopy procedures.Methods From December 2021 to February 2023,60 patients with central airway diseases underwent rigid bronchoscopy under general anesthesia,they were randomly divided into deep muscle relaxation group(group D,n = 30)and moderate muscle relaxation group(group M,n = 30).After induction of general anesthesia,the patients were inserted rigid bronchoscopy for jet ventilation,muscle relaxant was rocuronium in induction and maintenance.Train of four(TOF)stimulation was used to measure the depth of muscle relaxation in group M,and the TOF count was maintained at 1 or 2;In Group D,the depth of muscle relaxation was measured by post tetanic count(PTC),and the PTC was maintained at 1 or 2.After operation,Sugammadex antagonized residual muscle relaxation.Results There was no significant difference in operation time,recovery time and extubation time between the two groups(P＞0.05).The total operation time,operation pause time and anesthesia time in group D were shorter than those in group M,the dosage of muscle relaxant in group D was more than that in group M,the incidence of hypoxemia during surgery in group D was less than that in group M,the operators'satisfaction in group D was better than that in group M,and the arterial partial pressure of oxygen(PaO2)in group D was higher than that in group M at 15 min(T1)and 30 min(T2)after jet ventilation,the number of patients with postoperative sore throat in group D was less than that in group M,the differences were statistically significant(P＜0.05).Conclusion The application of deep muscle relaxation by rocuronium in rigid bronchoscopy procedures can improve the oxygenation effect of normal frequency jet ventilation,reduce the operation pause time and anesthesia time,improve the satisfaction of operators,antagonizing residual muscle relaxation with Sugammadex can relieve the worry of delayed recovery from deep muscle relaxation.关键词
深度肌松/硬质支气管镜/喷射通气/氧合/低氧血症/介入性肺病学Key words
deep muscle relaxation/rigid bronchoscopy/jet ventilation/oxygenation/hypoxemia/interventional pulmonology分类
医药卫生引用本文复制引用
裘宝玉,黄丽君,叶辉,俞万钧,彭卫东,任秋生..硬质支气管镜术中应用罗库溴铵行深度肌松对喷射通气氧合效果的影响[J].中国内镜杂志,2023,29(12):20-25,6.基金项目
浙江省医药卫生科技计划项目(No:2021KY332) （No:2021KY332）
