中国普通外科杂志2023，Vol.32Issue(11)：1797-1803,7.DOI:10.7659/j.issn.1005-6947.2023.11.019
分化型甲状腺癌颈部淋巴结转移相关分子的研究进展
Research progress of molecular signatures associated with cervical lymph node metastasis in differentiated thyroid carcinoma
摘要
Abstract
Differentiated thyroid carcinoma(DTC)exhibits an indolent progression and a favorable prognosis,but it is prone to early cervical lymph node metastasis(LNM),which is closely associated with postoperative recurrence and poor prognosis.High-resolution ultrasound,CT scanning,and fine-needle aspiration biopsy are commonly used methods for preoperative assessment of the presence and extent of cervical LNM.With the development of molecular biology techniques,significant progress has been made in the understanding of molecular mechanisms related to the prognosis of DTC.It holds the promise of providing new non-invasive and accurate ways to preoperatively assess cervical LNM,individualize surgical plans,and reduce unnecessary lymph node dissection.Here,the authors,based on current clinical research,summarize and discuss the relationship between molecular biomarkers and cervical LNM in DTC,as well as their potential value in diagnosis and prognosis.关键词
甲状腺肿瘤/淋巴转移/颈,生物标记/综述Key words
Thyroid Neoplasms/Lymphatic Metastasis/Neck,Biomarkers/Review分类
医药卫生引用本文复制引用
赵小慧,魏明辉,李正江,安常明..分化型甲状腺癌颈部淋巴结转移相关分子的研究进展[J].中国普通外科杂志,2023,32(11):1797-1803,7.基金项目
广东省深圳市"医疗卫生三名工程"基金项目资助(SZSM201911006). （SZSM201911006）
