中国人兽共患病学报2023,Vol.39Issue(11):1072-1079,8.DOI:10.3969/j.issn.1002-2694.2023.00.126
从代谢角度看冠状病毒与宿主的相互作用
The interaction between the coronavirus and the host from a metabolic point of view
摘要
Abstract
The emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)triggered the global pandemic of novel coronavirus pneumonia and brought the"coronavirus"into the public eye.It is well known that rapid replication of vi-ruses can cause drastic metabolism changes in host cell,and recent studies have found corresponding antiviral targets from these key changes.In this review,we focus on recent studies on the effects of coronavirus on host metabolism,including lipid metabolism,central carbon metabolism,amino acid metabolism etc.Identifying host cell metabolic induced viral infection not only helps to better understand virus-host interactions,but also helps to develop potential antiviral strategies by targeting meta-bolic alterations.关键词
冠状病毒/细胞代谢/药物靶点Key words
coronavirus/cellular metabolism/drug targets分类
医药卫生引用本文复制引用
黄梓鑫,周书亭,王哲..从代谢角度看冠状病毒与宿主的相互作用[J].中国人兽共患病学报,2023,39(11):1072-1079,8.基金项目
Supported by the National Key Research and Development Plans of China(No.2021YFD1800400).Wang Zi-xin and Zhou Shu-ting contributed equally to this paper.国家重点研发计划资助项目(No.2021YFD1800400) (No.2021YFD1800400)