中国输血杂志2023，Vol.36Issue(12)：1118-1123,6.DOI:10.13303/j.cjbt.issn.1004-549x.2023.12.009
术前肝功能对升主动脉手术患者围术期大量输血的预测价值
Predictive value of preoperative liver function for perioperative massive blood transfusion in patients undergoing as-cending aorta surgery
钱丽慧 1朱才民 1赵章生 1王磊 1周薇 1忻其乐 1马幼丽 1牧启田2
作者信息
- 1. 宁波大学附属李惠利医院,浙江 宁波 315040
- 2. 宁波大学附属第一医院
- 折叠
摘要
Abstract
Objective To explore the predictive value of preoperative liver function for massive blood transfusion(MBT)in patients undergoing ascending aorta surgery.Methods Data from 238 patients undergoing ascending aorta surger-y in the Department of Cardiovascular Surgery at The Affiliated Lihuili Hospital of Ningbo University were collected.Preoper-ative liver function tests were performed for all patients.Based on the perioperative transfusion volumes of red blood cell sus-pension,patients were divided into the MBT group,non-MBT group,and no blood transfusion(NBT)group.Clinical data during the perioperative period were compared among different groups.Receiver operating characteristic curve(ROC curve)analysis was used to assess the predictive value of liver function indicators for MBT and determine cut-off values.Results Com-pared with the non-MBT group and NBT group,the MBT group showed statistically significant differences in preoperative levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),direct bilirubin(DBIL),and serum albumin(SA)(P＜0.05).ROC curve analysis revealed that AST had the largest area under the curve(AUC)for predicting MBT,with a value of 0.723.ALT had the highest specificity for predicting MBT at 86.7%,and SA had the highest sensitivity at 89.7%.When AST＞28.50 U/L,ALT＞40.00 U/L,SA≤34.55 g/L,and DBIL＞4.25 μmol/L,there was a significant increase in the transfusion volume of various blood components and the incidence of MBT.Conclusion Preoperative liver function indi-cators(AST,ALT,SA,DBIL)have a moderate predictive value for MBT in patients undergoing ascending aorta surgery.关键词
肝功能/天门冬氨酸氨基转移酶/升主动脉手术/A型主动脉夹层/大量输血Key words
liver function/aspartate aminotransferase/ascending aortic surgery/type A aortic dissection/massive blood transfusion分类
临床医学引用本文复制引用
钱丽慧,朱才民,赵章生,王磊,周薇,忻其乐,马幼丽,牧启田..术前肝功能对升主动脉手术患者围术期大量输血的预测价值[J].中国输血杂志,2023,36(12):1118-1123,6.
