摘要
Abstract
Objective To explore the value of thrombelastogram(TEG)on monitoring the coagulation function and guid-ing blood transfusion in admitted patients in early stage of severe trauma.Methods A total of 96 patients in early stage of severe trauma were selected from Ezhou Central Hospital,and were divided into two groups using a random number table method,with 48 patients in each group.The control group was guided by four routine coagulation tests for blood transfusion,while the observation group was guided by TEG.The detection rate of trauma-induced coagulopathy,detection duration,blood infusion volume within 24 hours of admission,coagulation index levels at different time points after blood transfusion,length of hospital stay,ICU stay,and mortality rate between the two groups were compared.Results The detection rate of trauma-induced coagulopathy was 72.9%in the control group and 93.8%in the observation group(P＜0.05).The transfusion volume of fresh frozen plasma(U)and red blood cell(U)in the observation group within 24 hours of admission were significantly lower than those in the control group,which were(35.13±4.75)vs(45.17±6.54),(5.19±1.41)vs(7.08±1.32)(P＜0.05);the tranfusion volume of cryoprecipitate(U)and the rate of platelet transfusion in the observation group were signifi-cantly higher than those in the control group,which were(36.78±2.49)vs(24.84±3.92),79.2%vs 22.9%(P＜0.05).The APTT(s),PT(s),TT(s),R(min),and K(min)in the observation group 8 hours after blood transfusion were significant-ly lower than those in the control group,which were(58.16±10.39)vs(70.83±14.99),(15.44±3.22)vs(17.32±2.89),(21.39±4.51)vs(25.18±4.73),(13.03±3.29)vs(14.95±4.57),and(8.07±3.65)vs(10.54±5.14)(P＜0.05),while FIB(g/L),MA(mm),α(°),and Plt(×109/L)were higher than those in the control group,which were(2.02±0.46)vs(1.09±0.27),(35.56±11.88)vs(29.57±9.25),(40.07±13.34)vs(27.23±10.87),and(135.87±59.13)vs(108.17±52.08)(P＜0.05).Conclusion TEG can help monitoring the coagulation function in patients in early stage of severe trau-ma and guide the blood transfusion.关键词
血栓弹力图/临床用血/严重创伤Key words
thrombelastogram(TEG)/clinical blood use/severe trauma分类
临床医学
