中国输血杂志2023，Vol.36Issue(12)：1147-1151,5.DOI:10.13303/j.cjbt.issn.1004-549x.2023.12.016
献血人群对去白细胞悬浮红细胞保存期末溶血率的影响因素
Factors influencing hemolysis rate of leukocyte-reduced red blood cells at the end of preservation period in blood do-nors
张刘娟 1王心维 1庞栋 1潘阳春 1韦振兴 1李雄 1朱秋亭 1何汝汝 1张翙1
作者信息
摘要
Abstract
Objective To compare the current standards and explore the influencing factors for hemolysis rate of leuko-cyte-reduced red blood cells at the end of the preservation period,in order to formulate reasonable internal control indicators.Methods A retrospective analysis was performed on hemolysis rate of 427 samples of leukocyte-reduced red blood cells at the end of the preservation period in Nanning Blood Center from 2015 to 2022.Compared with the current standard for hemol-ysis rate at the end of the preservation period(GB 18469-2012 Quality Requirements for Whole Blood and Component Blood),the differences were analyzed,and the factors influncing the hemolysis rate were analyzed in terms of different blood donor groups.Results 1)Among the 427 samples,the hemolysis rate of 418(97.89%)did not exceed 0.4%,all lower than 0.8%;2)the hemolysis rate of the male group was higher than that of the female group;3)the hemolysis rate of the 18-29 years old group was lower than that of the 30-39 year old group and the 40-60 year old group,with statistically signifi-cant difference;4)in terms of occupation,the hemolysis rate of students was the lowest,and the differences between groups were statistically significant;5)no statistical significance was found in ethnicity and blood type.Conclusion Statistics indi-cated that gender,age,blood donation volume and occupation of blood donors were the influencing factors of hemolysis rate.The current standard is obviously higher in the qualified range of blood quality control in Nanning.It is advisable to formulate a reasonable quality control strategy with internal control index of hemolysis rate set＜0.4%,which is conducive to making accurate evaluation of internal quality control and ensuring blood safety.关键词
溶血率/去白细胞悬浮红细胞/质量标准/献血人群/影响因素/内控指标Key words
hemolysis rate/leukocyte-reduced red blood cells/quality standard/blood donors/influencing factors/in-ternal control indicators分类
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张刘娟,王心维,庞栋,潘阳春,韦振兴,李雄,朱秋亭,何汝汝,张翙..献血人群对去白细胞悬浮红细胞保存期末溶血率的影响因素[J].中国输血杂志,2023,36(12):1147-1151,5.
