中国实用妇科与产科杂志2023,Vol.39Issue(12):1160-1163,4.DOI:10.19538/j.fk2023120103
妊娠期B族链球菌阴道定植感染与母儿结局
Group B Streptococcus viginal colonization dur-ing pregnancy and the outcome of the mothers and infants
摘要
Abstract
Group B streptococcus(GBS)vaginal colo-nization during pregnancy refers to the carrier of GBS bacteria in the reproductive tract of pregnant women without any clinical symptoms.This infection can have a certain impact on the health of mothers and infants.For pregnant women,GBS vaginal colonization can cause diseases under certain conditions,such as As-ymptomatic bacteriuria,cystitis,preterm labor,and even postpartum puerperal infection.During child birth,bacteria can spread to fetuses and newborns through ascending and vertical infections,leading to serious complications including pneumonia,meningitis,and sepsis,becoming a common cause of neonatal death in many countries.Many countries,including China,have established strategies for prenatal GBS screening and preventive antibiotic treatment,but there are still certain limitations.The detection of GBS virulence genes and the development of targeted vaccines will be the means to improve maternal and fetal outcomes and achieve best economic and health benefits in the future.关键词
妊娠期/B族链球菌定植感染/妊娠结局Key words
pregnancy/group B streptococcus colo-nization/pregnancy outcomes分类
医药卫生引用本文复制引用
黄振宇,张蕾,曾桢..妊娠期B族链球菌阴道定植感染与母儿结局[J].中国实用妇科与产科杂志,2023,39(12):1160-1163,4.基金项目
国家自然科学基金重点仪器研发项目(61927819) (61927819)
北京市培育计划(PX2022039) (PX2022039)
清华大学精准医学院优先项目(10001020109) (10001020109)
清华大学精准医学院重点实验室(20219990012) (20219990012)