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肉牛羊消化道寄生蠕虫耐药性研究进展

李梦玥 贾旭晨 洪炀 朱怡平 段云芳 庹世友 王子璇 李靖

中国兽医杂志2023,Vol.59Issue(11):85-89,5.
中国兽医杂志2023,Vol.59Issue(11):85-89,5.

肉牛羊消化道寄生蠕虫耐药性研究进展

Research Progress on Anthelmintic Resistance of Gastrointestinal Parasite in Beef and Sheep

李梦玥 1贾旭晨 1洪炀 2朱怡平 1段云芳 3庹世友 4王子璇 1李靖5

作者信息

  • 1. 中国农业大学动物医学院兽医公共卫生安全全国重点实验室,北京海淀 100193
  • 2. 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心),国家卫生健康委员会寄生虫病原与媒介生物学重点实验室,世界卫生组织热带病合作中心,国家级热带病国际联合研究中心,上海卢湾 200025
  • 3. 西藏自治区应急管理厅,西藏拉萨850011
  • 4. 喀什地区畜牧研究中心(安格斯牛研究中心),新疆喀什 844000
  • 5. 中国农业大学动物医学院兽医公共卫生安全全国重点实验室,北京海淀 100193||喀什地区畜牧研究中心(安格斯牛研究中心),新疆喀什 844000
  • 折叠

摘要

Abstract

The escalating problem of gastrointestinal parasite drug resistance in beef and sheep worldwide is attributed to the pro-longed use of a limited range of anthelmintic drugs.This article reviews the current status and mechanisms of gastrointestinal parasite anthelmintic resistance in beef and sheep,analyzing factors such as gene mutations,survival pressure,and drug usage that contribute to the increasing frequency of resistant genes.The advantages and disadvantages of various detection methods,including fecal egg count reduction tests,in vitro assays,and molecular detection,are summarized to provide valuable references for anthelmintic resist-ance detection in research and practical applications.Feasible measures to alleviate the emergence of anthelmintic resistance are pro-posed,such as rational drug use to establish"refuges",development of novel anthelmintic drugs,and improved feeding manage-ment.The aim of this article is to raise awareness of gastrointestinal parasite anthelmintic resistance in the beef and sheep industry,providing a basis for precise and efficient anthelmintic resistance detection and mitigation,and ultimately promoting the scientific and healthy breeding practices of beef and sheep to enhance the high-quality development of the industry.

关键词

消化道寄生虫/驱虫药物/耐药性/肉牛/肉羊

Key words

gastrointestinal parasites/anthelmintic drugs/drug resistance/beef/sheep

分类

农业科技

引用本文复制引用

李梦玥,贾旭晨,洪炀,朱怡平,段云芳,庹世友,王子璇,李靖..肉牛羊消化道寄生蠕虫耐药性研究进展[J].中国兽医杂志,2023,59(11):85-89,5.

基金项目

新疆维吾尔自治区重点研发计划项目(2022B02056-2) (2022B02056-2)

中国兽医杂志

OA北大核心

0529-6005

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