中国畜牧兽医2023，Vol.50Issue(12)：4935-4946,12.DOI:10.16431/j.cnki.1671-7236.2023.12.016
选择信号分析及其对绵羊功能基因的挖掘进展
Advance on Selection Signal Analysis and Its Exploration for Functional Genes in Sheep
摘要
Abstract
Through long-term natural and artificial selection,sheep have developed a rich and diverse variety of breeds that provide humans with meat,milk,wool,fur and other living items.Selection is accompanied by the generation of selection signals,such as population differentiation,decreased genomic diversity and the presence of high-frequency alleles in regions with long-range extended haplotype purity in selected regions.For different types of selection signals,corresponding analysis methods have been derived,such as population differentiation-based analysis,genomic heterozygosity-based analysis,haplotype and linkage disequilibrium-based analysis,and allele frequency profile-based analysis.In recent years,with the development of high-throughput sequencing technology,researchers have been able to mine a large number of functional genes associated with economic traits by performing selection signal analysis in sheep,providing more genetic information for sheep molecular breeding.The author introduces the classification and further presents the advances in utilizing these methods to screen sheep functional genes,the prospects of application and research are predicated on selection signal analysis,which provides valuable information for further applied research of selection signal analysis in sheep genetic breeding.关键词
绵羊/选择信号/功能基因Key words
sheep/selection signals/functional genes分类
农业科技引用本文复制引用
张彦威,于丽娟,徐新明,阿米妮古丽·阿不来孜,谢梦婉,唐丽苹,郑培宇,狄江..选择信号分析及其对绵羊功能基因的挖掘进展[J].中国畜牧兽医,2023,50(12):4935-4946,12.基金项目
新疆自治区重点实验室开放课题(2020D04035) （2020D04035）
国家重点研发计划课题(2021YFD1200901) （2021YFD1200901）
天山创新团队计划(2022D14018) （2022D14018）
