中国畜牧兽医2023，Vol.50Issue(12)：5194-5203,10.DOI:10.16431/j.cnki.1671-7236.2023.12.040
玉米赤霉烯酮在动物体内的代谢与分子毒性研究进展
Research Progress on Metabolism and Toxicity of Zearalenone in Animals
摘要
Abstract
Zearalenone(ZEA)is a mycotoxin produced by the fungi of Fusarium genera,which widely contaminates corn,wheat,barley,and other grains.After metabolism and conversion,ZEA can be distributed throughout the body via the bloodstream,causing damage in liver,kidney,uterus,testis and other organs through estrogenic effects,oxidative damage,cell apoptosis,etc.In recent years,the contamination of ZEA in crops not only poses serious challenges to livestock farming and feed industries but also threatens human health.A deep comprehension of the metabolism and toxic mechanism in animals is particularly essential for developing new prevention strategies to mitigate the negative impacts of ZEA.The author focuses on the absorption,distribution,metabolism and molecular toxicology of ZEA to clarify its toxic mechanism in animals.关键词
玉米赤霉烯酮/代谢转化/分子毒性Key words
zearalenone/metabolism/molecular toxicology分类
农业科技引用本文复制引用
邓子锋,王利娟,吴希强,杨宏辉,李廷元,汪玲玲..玉米赤霉烯酮在动物体内的代谢与分子毒性研究进展[J].中国畜牧兽医,2023,50(12):5194-5203,10.基金项目
广东省自然科学基金-面上项目(2021A1515011170) （2021A1515011170）
