摘要
Abstract
Objective:To explore the clinical effect of Iron Sucrose combined with erythropoietin(EPO)in the treatment of renal anemia in patients with chronic renal failure(CRF).Method:A total of 60 patients with CRF renal anemia admitted to Jiujiang NO.1 People's Hospital from March 2021 to June 2022 were selected as the research objects.According to the random number table method,they were divided into the control group and the observation group,with 30 cases in each group.The control group was treated with EPO,and the observation group was treated with Iron Sucrose on the basis of the control group.The time of anemia correction,iron metabolism related indexes,treatment effect and the incidence of adverse reactions were compared between the two groups.Result:The time of anemia correction in the observation group was shorter than the control group(P<0.05).The dose of EPO used in the observation group was less than that in the control group,and the incidence of adverse reactions in the observation group was 6.67%,which was lower than 26.67% in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in iron metabolism indexes between the two groups(P>0.05);after treatment,all iron metabolism indexes were improved,and the iron metabolism related indexes in the observation group were higher than those in the control group(P<0.05);the total effective rate of the observation group was 93.33%,which was higher than 70.00% of the control group,the difference was statistically significant(P<0.05).Conclusion:EPO combined with Iron Sucrose in the treatment of renal anemia in patients with CRF has outstanding effect in improving the clinical symptoms and anemia related indicators,and is safe and reliable.关键词
蔗糖铁/慢性肾衰竭/肾性贫血/血红蛋白/红细胞压积Key words
Iron Sucrose/Chronic renal failure/Renal anemia/Hemoglobin/Hematocrit