中国医学装备2023，Vol.20Issue(12)：42-45,4.DOI:10.3969/J.ISSN.1672-8270.2023.12.009
口服复方泛影葡胺对女性盆腔肿瘤患者放射治疗计划剂量及验证通过率的影响
Effect of oral compound meglumine diatrizoate on the dose and verification pass rate of radiotherapy plan of female patients with pelvic tumor
吴青南 1杨雨岩 1孙博1
作者信息
- 1. 北京大学国际医院放疗科 北京 102206
- 折叠
摘要
Abstract
Objective:To explore the effect of oral contrast agent on the dose distribution and verification pass rate of radiotherapy plan when female patients with pelvic tumor underwent oral contrast agent to assist the delineations for tumors and organ at risk(OAR).Methods:A total of 15 female patients with pelvic tumor were selected.The original computed tomography(CT)images of each patient were the images with oral contrast agent.Based on these images,a 7-field static intensity-modulated radiotherapy plan was designed as plan 1.The intestinal CT values of the original images were modified to simulate the situations without oral contrast agent to obtain new images.The same optimization parameters of plan 1 was used to design a 7-field static intensity-modulated radiotherapy plan as plan 2.The two kinds of plans were normalized to a degree which 95%of volume was covered by 100%dose at the central point of target region.The 9 parameters of dose distribution included the maximum dose(Dmax),and two verification parameters were calculated as statistical method,and then,the effect of contrast agent was assessed.Results:The Dmax values of the target regions of plan 1 and plan 2 were respectively(5457.9±46.41)and(5455.8±46.33).The mean dose(Dmean)values of them were respectively(5185.4±24.39)and(5189.4±22.78).The conformity index(CI)values of them were respectively 1.03±0.03 and(1.03±0.03).The γ(3%/3 mm)pass rates of them were respectively(99.17±0.44)and(98.93±0.81)(P=0.177).The γ(2%/2 mm)pass rates of them were(95.46±1.27)and(94.88±1.87)(P=0.143).The differences of the dose and verification parameters between the designed two plans on the basis of the images with and without oral contrast agent were not statistical significance(P>0.05).Conclusion:Contrast agent does not have statistical effect on the dose distribution and verification pass rate of static intensity-modulated radiotherapy plan for female patients with pelvic tumor.关键词
调强放射治疗/盆腔肿瘤/口服造影剂/剂量比较/剂量验证Key words
Intensity-modulated radiotherapy/Pelvic tumor/Contrast agent/Dose contrast/Dose verification分类
临床医学引用本文复制引用
吴青南,杨雨岩,孙博..口服复方泛影葡胺对女性盆腔肿瘤患者放射治疗计划剂量及验证通过率的影响[J].中国医学装备,2023,20(12):42-45,4.
