中成药2023，Vol.45Issue(12)：3980-3986,7.DOI:10.3969/j.issn.1001-1528.2023.12.021
交趾黄檀心材化学成分的研究
Chemical constituents from the heartwood of Dalbergia cochinchinensis
摘要
Abstract
AIM To study the chemical constituents from the heartwood of Dalbergia cochinchinensis Pierre ex Laness.METHODS The 70%ethanol extract from the heartwood of D.cochinchinensis was isolated and purified by silica gel,Sephadex LH-20 and semi-preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULT Twenty-three compounds were isolated and identified as 3-O-acetylbetulin aldehyde(1),2,2'-oxybis(1,4-di-tert-butylbenzene)(2),ethyl 4-hydroxybenzoate(3),1-acetyl-β-carboline(4),7-hydroxydihydroflavone(5),palmic acid(6),hexadeca-4,7-diene(7),linoleic acid(8),methyl 4-hydroxybenzoate(9),2-(2-hydroxy-1-methyl-2-phenythyl)-4,5-dimethoxyphenol(10),2-methoxy-3-hydroxyxanthone(11),dibutyl terephthalate(12),6,4'-dihydroxy-7-methoxyflavan(13),pteroyanin G(14),benzoic acid,4-ethoxy-2-methoxy-,methyl ester(15),liquiritigenin(16),4,2',5'-trihydroxy-4'-methoxychalcone(17),7-hydroxy-6-methoxyflavone(18),6,4'-dihydroxy-7-methoxyflavone(19),2'-hydroxyformonetin(20),3'-methoxyformonetin(21),3'-hydroxyformonetin(22),6,7,4'-trihydroxyflavanone(23).CONCLUSION Compounds 2,4 are isolated from genus Dalbergia for the first time.Compounds 6-8,19,21 are isolated from this plant for the first time.关键词
交趾黄檀/心材/化学成分/分离鉴定Key words
Dalbergia cochinchinensis Pierre ex Laness/heartwood/chemical constituents/isolation and identification分类
医药卫生引用本文复制引用
郑启万,任佳慧,刘洋,危先文,孟晓伟,杨丽,陈兰英,刘荣华..交趾黄檀心材化学成分的研究[J].中成药,2023,45(12):3980-3986,7.基金项目
国家自然科学基金(82160732) （82160732）
国家重点研发计划课题(2018YFC1706102) （2018YFC1706102）
江西省自然科学基金(20202BABL216072) （20202BABL216072）
