中成药2023，Vol.45Issue(12)：3987-3994,8.DOI:10.3969/j.issn.1001-1528.2023.12.022
莲须化学成分的研究
Chemical constituents from Nelumbinis Stamen
摘要
Abstract
AIM To study the chemical constituents from Nelumbinis Stamen.METHODS The methanol extract from Nelumbinis Stamen was isolated and purified by silica gel,C8 reversed phase column,Sephadex LH-20,preparative TLC and preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-one compounds were isolated and identified as erythrodiol(1),erythordiol-3-acetate(2),2α-hydroxy-oleanolic acid(3),oleanolic acid(4),4-epi-hederagenin(5),4-epi-hederagenin methyl ester(6),28α-homo-β-amyrin acetate(7),betulinic acid(8),24-ketocholesterol(9),7β-hydroxy-sitosterol(10),7α-hydroxy-sitosterol(11),3β-hydroxy-stigmast-5-en-7-one(12),(3β,5α,6β,22E)-6-methoxyergosta-7,22-diene-3,5-diol(13),dankasterone A(14),demethylincisterol A3(15),β-sitostenone(16),β-sitosterol(17),quercetin(18),isorhamnetin(19),kaempferol(20),luteolin(21).CONCLUSION Compounds 2,4-15 are isolated from genus Nelumbo for the first time.Compound 16 is isolated from this plants for the first time.关键词
莲须/化学成分/分离鉴定Key words
Nelumbinis Stamen/chemical constituents/isolation and identification分类
医药卫生引用本文复制引用
李玥,吴弢..莲须化学成分的研究[J].中成药,2023,45(12):3987-3994,8.基金项目
国家自然科学基金资助项目(81973475) （81973475）
