中成药2023，Vol.45Issue(12)：4024-4029,6.DOI:10.3969/j.issn.1001-1528.2023.12.028
小蓟TLC鉴别方法优化及小蓟炭"炒炭存性"内在表征研究
Optimization of TLC identification for Cirsii Herba and research on changes in quality properties "carbonizing retains characteristics" of its charred product
摘要
Abstract
AIM To optimize the TLC identification method for Cirsii Herba and to study the changes in quality properties"carbonizing retains characteristics"of Cirsii Herba Carbonisata.METHODS After the improvement of thin layer plate and solvent in the TLC identification based on the Chinese Pharmacopoeia 2020 Edition for Cirsii Herba,Cirsii Herba Carbonisata had its TLC identification method and UPLC fingerprint established for the determination of its content of buddleoside and acacetin as well.RESULTS We used silica gel G plate,and the solvent of toluene-acetone-formic acid-methanol(6 ∶ 3 ∶ 0.5 ∶ 2.5)for TLC identification of Cirsii Herba.The content variations of buddleoside and acacetin in Cirsii Herba and its differently charred products were consistent with the result of the TLC identification.CONCLUSION The improved TLC identification method for Cirsii Herba is of lower cost and less solvent toxicity compared to the method in the Chinese Pharmacopoeia 2020 Edition,and can identify the changes in quality properties"carbonizing retains characteristics"of differently charred Cirsii Herba,therefore it can be used to control the quality of Cirsii Herba Carbonisata in the market.关键词
小蓟/小蓟炭/TLC/炒炭存性Key words
Cirsii Herba/Cirsii Herba Carbonisata/TLC identification/carbonizing retains characteristics分类
医药卫生引用本文复制引用
卢琪,张天泽,朱娟娟,曲珍妮,徐春梦,戴衍朋,石典花..小蓟TLC鉴别方法优化及小蓟炭"炒炭存性"内在表征研究[J].中成药,2023,45(12):4024-4029,6.基金项目
国家中医药管理局中药炮制技术传承基地建设项目(2022) （2022）
山东省自然基金(ZR2023MH114) （ZR2023MH114）
山东省中医药科技发展计划项目(Q-2022085,Z-2022086T) （Q-2022085,Z-2022086T）
山东省中医药研究院孵化基金(2021SACM-2) （2021SACM-2）
山东省中医药特色疗法挖掘整理推广应用项目(2021) （2021）
山东省中医药高层次人才培育项目(鲁卫中医药科教字[2021]6号) （鲁卫中医药科教字[2021]6号）
齐鲁医派中医学术流派传承项目(2021) （2021）
