大学化学2023，Vol.38Issue(11)：195-205,11.DOI:10.3866/PKU.DXHX202304015
Cu(Ⅰ)/TEMPO体系催化空气氧化苄醇
Air Oxidation of Benzyl Alcohol Catalyzed by Cu(Ⅰ)/TEMPO System:An Comprehensive Experiment Design of Organic Chemistry
摘要
Abstract
The oxidation of benzyl alcoyhol to benzaldehyde plays an important role in teaching organic chemistry.However,it is often difficult to enter basic university organic chemistry experimental teaching classes because of the unfriendly environment.In this paper,a comprehensive experiment in organic chemistry is introduced.Benzyl alcohol was efficiently oxidized to benzaldehyde in less than 30 min at room temperature using cuprous chloride,2,2'-bipyridine(bpy),N-methylimidazole(NMI),and 2,2,6,6-tetramethylpiperidine oxide(TEMPO)as catalysts,air as oxidant,and acetone as solvent.The optimized combined catalytic system can indicate the endpoint of the reaction through color mutation;it can miniaturize the experiment,shorten the reaction time,and reduce experimental cost.Extensive experiments were conducted on benzyl alcohol compounds with different electrical properties,and the reaction exhibited wide adaptability.To some extent,this experiment compensates for the lack of experimental teaching resources for aromatic aldehyde synthesis in college chemistry teaching experiments.关键词
有机化学综合实验/空气氧化/芳香醛/结构表征Key words
Comprehensive experiment of organic chemistry/Air oxidation/Aromatic aldehydes/Structural characterization分类
社会科学引用本文复制引用
奉强,王思宇,李倩意,王晓月,何冰..Cu(Ⅰ)/TEMPO体系催化空气氧化苄醇[J].大学化学,2023,38(11):195-205,11.基金项目
四川省科技计划资助(2023NSFSC0101) （2023NSFSC0101）
四川省大学生创新创业项目(S202114389166) （S202114389166）
