大学化学2023，Vol.38Issue(11)：223-229,7.DOI:10.3866/PKU.DXHX202304058
有机化学实验的副产物分析引导实验创新与科研素养培育
Side Reaction Products Analysis of Organic Chemistry Experiments to Guide Experimental Innovation and Improve Scientific Research Literacy:Synthesis of 4-Phenylbutyl-2-ketone
摘要
Abstract
The synthesis of 4-phenyl buty-2-ketone from ethyl acetoacetate and benzyl chloride is a classical organic chemistry experiment,but the yield is only 20％-30％in practical teaching.This paper records the process of teachers guiding students to separate the byproduct in the experiment,determines it as 2,2-dibenzyl-3-oxybutyrate,analyzes the causes of the byproduct,and inspires the students to innovate the experimental method to increase the yield to 57.5％.This teaching practice not only guides students with regard to experimental innovation but also improves the scientific research literacy of students.关键词
4-苯基丁-2-酮/实验创新/提升产率/科研素养Key words
4-Phenyl buty-2-ketone/Experimental innovation/Improvement of reaction yield/Scientific research literacy分类
社会科学引用本文复制引用
陈建军,曹月洋,陈万红,黄国生,高坤..有机化学实验的副产物分析引导实验创新与科研素养培育[J].大学化学,2023,38(11):223-229,7.基金项目
兰州大学教育教学改革研究项目(JYXM-2020-05) （JYXM-2020-05）
国家自然科学基金项目(81973193,22277045) （81973193,22277045）
