口腔疾病防治2024，Vol.32Issue(2)：81-88,8.DOI:10.12016/j.issn.2096-1456.2024.02.001
血浆基质在牙髓根尖周病治疗中的应用
The applications of the plasma matrix in the treatments of dental pulp and periapical diseases
摘要
Abstract
The plasma matrix is a kind of autologous blood conduct.It has been widely used in maxillofacial tissue regeneration,skin cosmetology and some other fields.Recently,to preserve the dental pulp as well as the teeth,pulp re-generation therapy and apical surgery have become increasingly important as well as the applications of bioactive materi-als.As a kind of autologous bioactive material,the plasma matrix has some natural advantages as it is easy to obtain and malleable.The plasma matrix can be used in the following cases:①pulp revascularization of young permanent teeth with open apical foramina that cannot stimulate apical bleeding;② apical barrier surgery with bone defects and large ar-ea perforation repair with bone defects or root sidewall repair surgery;③ apical surgeries of teeth with large area of api-cal lesions,with or without periodontal diseases.The plasma matrix is a product derived from our blood,and there are no obvious contraindications for its use.Several systematic reviews have shown that the plasma matrix can effectively promote the regenerative repair of dental pulp in patients with periapical diseases.However,the applications of plasma matrix are different because its characteristics are affected by different preparation methods.In addition,there is still a lack of long-term clinical researches on the plasma matrix,and the histological evidences are difficult to obtain,so a large number of in vitro and in vivo experimental studies are still needed.This article will describe the applications of different kinds of plasma matrix for dental pulp regeneration and bone tissue regeneration in apical surgeries to provide references for clinicians in indication selection and prognosis evaluation.关键词
血浆基质/牙髓血运重建术/牙髓再生修复/根尖手术/牙体硬组织修复/根尖诱导成形/髓室底穿孔修补/富血小板血浆/富血小板纤维蛋白/浓缩生长因子Key words
plasma matrix/pulp revascularization/pulp regeneration/apical surgery/repair of dental hard tissue/apexification/furcation perforation repair/platelet-rich plasma/platelet-rich fibrin/concentrated growth factor分类
医药卫生引用本文复制引用
杨雪超,李文芝..血浆基质在牙髓根尖周病治疗中的应用[J].口腔疾病防治,2024,32(2):81-88,8.基金项目
广东省自然科学基金项目(2023A1515012777) （2023A1515012777）
广东省科技计划项目(2017A050501054) （2017A050501054）
广州市临床特色技术项目(2023C-TS58)This study was supported by the grants from the National Science Fund of Guangdong Province(No.2023A1515012777) （2023C-TS58）
Science and Technology Program of Guangdong Province(No.2017A050501054) （No.2017A050501054）
Clinical Characteristic Technology Program of Guangzhou(No.2023C-TS58). （No.2023C-TS58）
