国际医药卫生导报2023，Vol.29Issue(24)：3542-3545,4.DOI:10.3760/cma.j.issn.1007-1245.2023.24.004
白细胞相关免疫球蛋白样受体1在糖尿病中的研究现状
Leukocyte-associated immunoglobulin-like receptor 1 in diabetes
杨玲瑜 1金勇君1
作者信息
- 1. 滨州医学院烟台附属医院内分泌科,烟台 264000
- 折叠
摘要
Abstract
Leukocyte-associated immunoglobulin-like receptor-1(LAIR-1)is an immune inhibitory receptor that mediates immune suppression.It can affect the occurrence and development of various metabolic and immune diseases by regulating inflammatory responses.Type 2 diabetes mellitus is the most common form of disease that leads to insulin production defects.It is now recognized that the inflammatory response is a result of immune response to high blood glucose levels.This low-grade chronic inflammation damages the beta cells of the pancreas and leads to insufficient insulin secretion,resulting in high blood glucose.This review elaborates on the mechanism of inflammation in type 2 diabetes mellitus and the impact of LAIR-1 on its development.关键词
2型糖尿病/白细胞相关免疫球蛋白样受体1/炎症/胰岛素抵抗/综述Key words
Type 2 diabetes mellitus/Leukocyte-associated immunoglobulin-like receptor-1/Inflammation/Insulin resistance/Review引用本文复制引用
杨玲瑜,金勇君..白细胞相关免疫球蛋白样受体1在糖尿病中的研究现状[J].国际医药卫生导报,2023,29(24):3542-3545,4.
