口腔疾病防治2024，Vol.32Issue(2)：137-142,6.DOI:10.12016/j.issn.2096-1456.2024.02.008
儿童苔藓样肉芽肿性口炎1例报道及文献回顾
Childhood lichenoid granulomatous stomatitis:a case report and literature review
摘要
Abstract
Objective To investigate the classification,clinical manifestations,diagnosis,differential diagnosis and treatment of oral lichenoid lesions and provide a reference for clinical practice.Methods Hospital ethical approval and patient informed consent were obtained.We report a case of oral lichenoid lesion in children and review the diagno-sis and treatment of oral lichenoid damage in the literature.Results The patient experienced repeated rupture of the dorsal surface of the tongue with pain for more than 3 years.There was a large area of tongue back surface erosion with an irregular shape,surrounded by pearly-white lines.The left erosive area was accompanied by tissue hyperplasia,which was approximately 1.5 cm × 2.0 cm,with tough texture and broad masses.The pathological diagnosis of the pa-tient was oral lichenoid lesion.After biopsy of the dorsal surface of the tongue,the pathological diagnosis of the patient was granulomatous inflammation.The final diagnosis of lichenoid granulomatous stomatitis was made on the basis of the patient's intraoral damage features,systemic history,medication history and histopathological findings.A review of the literature suggests that oral lichenoid lesions have an unknown etiology and need to be clinically differentiated from oral lichen planus,oral lichenoid drug reactions,oral lichenoid contact damage and chronic ulcerative stomatitis.The clini-cal treatment of oral lichen planus is based on the topical and/or systemic use of glucocorticoids.Conclusion There are still no uniform criteria for the classification and diagnosis of oral lichenoid lesions.They rely mainly on history tak-ing,clinical manifestations and histopathological findings,and the treatment is mainly based on the topical and/or sys-temic use of glucocorticoids.关键词
口腔苔藓样损害/苔藓样肉芽肿性口炎/口腔扁平苔藓/口腔苔藓样药物反应/口腔苔藓样接触性损害/移植物抗宿主病相关性苔藓样损害/慢性溃疡性口炎/类天疱疮样扁平苔藓/儿童/糖皮质激素分类
医药卫生引用本文复制引用
徐婧,夏荣辉,杨涟漪,沈雪敏,杜观环..儿童苔藓样肉芽肿性口炎1例报道及文献回顾[J].口腔疾病防治,2024,32(2):137-142,6.基金项目
国家自然科学基金项目(82101008) （82101008）
上海交通大学医学院附属第九人民医院医院管理研究项目(YGB202115)This study was supported by grants from the National Natural Science Foundation of China(No.82101008),Hospital Management Research Project of Shanghai Ninth People's Hospital,College of Stomatology,Shanghai Jiao Tong Univer-sity School of Medicine-Teaching Category(No.YGB202115). （YGB202115）
