国际口腔医学杂志2024，Vol.51Issue(1)：107-115,9.DOI:10.7518/gjkq.2024004
生物可降解镁基材料在颅颌面外科的应用及其研究进展
Applications and research progress of biodegradable magnesium-based materials in craniomaxillofacial surgery
摘要
Abstract
As a new generation of bone-implant materials,biodegradable magnesium-based materials show potential application in craniomaxillofacial surgery.Compared with traditional bone-implant materials,magnesium-based materials have excellent degradability,biocompatibility,mechanical properties,and osteogenic-promoting ability.The degradation of Mg implants leads to the production of magnesium ions,which have antiapoptosis and anti-inflammatory functions.Magnesium ions can also promote the healing of fractures and bone defects.Many studies have applied biodegradable magnesium-based materials to the internal fixation of craniomaxillofacial fractures,bone-substitute applications,guided bone regeneration,drug delivery,and implant surface coating.Results reveal that this kind of materials can provide stable support for bone healing and play a suitable role in osteogenic promoting.Magnesium-based materials also demonstrate potential in other fields,such as dental-tissue engineering and promotion of soft-tissue healing.All these findings indicate the importance of magnesium-based materials.关键词
生物可降解镁基材料/骨内固定/引导骨再生技术/骨替代材料/药物负载/镁涂层Key words
biodegradable magnesium-based material/internal fixation/guided bone regeneration/bone substitutes/drug delivery system/magnesium coating分类
口腔医学引用本文复制引用
常欣楠,刘磊..生物可降解镁基材料在颅颌面外科的应用及其研究进展[J].国际口腔医学杂志,2024,51(1):107-115,9.基金项目
Applied Basic Research Project of Sichuan Provincial Science and Technology Program(2020YJ0278) 四川省科技计划应用基础研究项目(2020YJ0278) （2020YJ0278）
