国际医药卫生导报2023，Vol.29Issue(24)：3700-3704,5.DOI:10.3760/cma.j.issn.1007-1245.2023.24.038
空氧混合温湿化氧疗在小婴儿类百日咳中的应用研究
Air-entrained warm humidity oxygen therapy for infants with pertussis syndrome
摘要
Abstract
Objective To observe the effect of air-entrained warm humidity oxygen therapy for infants with pertussis syndrome.Methods This study is a single center and controlled experiment.Fifty infants with pertussis syndrome admitted to Department of Pediatrics,Shunde Hospital of Southern Medical University were selected as the study objects and were divided into a control group and an observation group,with 25 cases in each group.The cases in the control group were selected from January 2020 to March 2021,including 17 males and 8 females who were(3.84± 2.96)months old,and took existing and traditional treatment and nursing measures.The cases in the observation group were selected from April 2021 to June 2022,including 14 males and 11 females who were(3.69±2.98)months old;on the basis of the treatment and nursing in the control group,the observation group took air-entrained warm humidity oxygen therapy.The oxygen saturations(SPO2),respiratory rates,sputum viscosities 48 and 72 h after the intervention,scab formation,and spasmodic cough relief times were compared between the two groups.The incidence of adverse reactions in the observation group was calculated.x2 test,t test,analysis of variance of multivariate repeated measurement,and non-parameter rank sum test were used for the statistical comparisons.Results The SPO2 increased with the intervention time,and the respiratory rate decreased as the intervention time prolonged in both groups(all P＜0.05).As the intervention time prolonged,the SPO2 in the observation group was higher than that in the control group(P＜0.05),and there was no statistical difference in the respiratory rate between the two groups(P＞0.05).Forty-eight and 72 h after the intervention,the numbers of cases of sputum viscosity(Ⅰ degree)in the observation group was higher than those in the control group(7 cases vs.1 case and 17 cases vs.3 cases),and the numbers of cases of sputum viscosity(Ⅲ degree)in the observation group were lower than those in the control group(4 case vs.18 cases and 1 case vs.15 cases),indicating that the sputum dilution effect in the observation group was better.The relief time of spasmodic cough in the observation group was significantly better than that in the control group[(4.32±1.18)d vs.(7.24± 2.02)d;P＜0.05].No adverse reactions,such as respiratory arrest,phlegm blockage,and pressure-associated skin injury,occurred in the observation group.Conclusion Air-entrained warm humidity oxygen therapy can effectively improve the airway environment of infants with pertussis syndrome and promote their recovery,and is safe.关键词
空氧混合/温湿化氧疗/类百日咳/小婴儿Key words
Air-entrainment/Warm humidification oxygen therapy/Pertussis syndrome/Infants引用本文复制引用
袁玲好,王晓云,李淑欢,饶宝玉..空氧混合温湿化氧疗在小婴儿类百日咳中的应用研究[J].国际医药卫生导报,2023,29(24):3700-3704,5.基金项目
佛山市卫生健康局医学科研项目(20210119)Medical Research Project of Foshan Health Bureau(20210119) （20210119）
