赣南医学院学报2023，Vol.43Issue(11)：1097-1101,5.DOI:10.3969/j.issn.1001-5779.2023.11.001
新辅助化疗后乳腺癌患者乳房病理完全缓解及腋窝淋巴结非病理完全缓解相关临床研究
Clinical study on breast pCR and axillary lymph node non-pCR in patients with breast cancer after neoadjuvant chemotherapy
摘要
Abstract
Objective:To analyze the survival prognosis and related risk factors of breast lesion which recahed pathologic complete response(pCR)and axillary metastatic lymph node,and got non-pCR in patients with breast cancer after neo-adjuvant chemotherapy(NACT).Methods:The postoperative pathological data and follow-up of breast cancer patients(53 cases)treated with neoadjuvant chemotherapy in The First Affiliated Hospital of Gannan Medical University from July 2015 to July 2019 were analyzed.They were divided into Group A(31 cases,breast lesion non-pCR and axillary metastatic lymph node pCR)and Group B(22 cases,pCR and axillary metastatic lymph node non-pCR).Results:Age,menopausal status,and tumour size between the two groups were with no statistical significance(P＞0.05);the differ-ence in disease types was with statistical significance(P＜0.05).Patients in Group A were mainly Her-2 positive;pa-tients in Group B were manly triple negative.The 2-year recurrence rate in Group A was 16.1%,lower than that of Group B(68.2%).The survival time in Group A was longer than that of Group B,the difference was statistically significant(P＜0.001).Axillary lymph node staging and tumor size were the risk factors of tumour progression in Group B(P＜0.001).The higher the lymph node staging of axillary metastasis,the shorter the progression-free-survival(P＜0.05).Conclusion:The survival prognosis of breast cancer patients with breast pCR and axillary metastatic lymph node non-pCR after neoadjuvant chemotherapy is worse with worse survival prognosis.Axillary lymph node staging and tumor size are the risk factors of thedisease progress of these patents.关键词
乳腺癌/新辅助化疗/病理完全缓解/腋窝淋巴结/无进展生存期Key words
Breast cancer/Neoadjuvant chemotherapy/Pathologic complete response/Axillary node/Progression free survival分类
医药卫生引用本文复制引用
赖闺娥,林志琴,刘凤恩..新辅助化疗后乳腺癌患者乳房病理完全缓解及腋窝淋巴结非病理完全缓解相关临床研究[J].赣南医学院学报,2023,43(11):1097-1101,5.基金项目
江西省卫生健康委员会科技计划项目(20204490) （20204490）
