摘要
Abstract
Objective To study PCT α1 The correlation between the levels of acid glycoprotein and haptoglobin and the severity of acute COPD.Methods 70 patients with acute COPD were selected as the study subjects.According to the severity of the disease,they were divided into stable COPD group of 34 patients and acute exacerbation(AECOPD)group of 36 patients,and 40 volunteers who came to our hospital for health examination at the same time were selected as the con-trol group.Detection of serum by enzyme-linked immunosorbent assay α1 Acid glycoprotein(α1-AG)level,the level of procal-citonin(PCT)was detected by immunofluorescence double antibody sandwich method,the level of serum haptoglobin(HPT)was measured by immune scattering rate turbidimetry,and the level of forced vital capacity(FVC)and forced expiratory volume in one second(FEV1)were measured by pulmonary function meter;Pearson was used to analyze pulmonary function indicators and serum PCT α1-Correlation of AG and HPT.Results Serum PCT α1-AG and HPT levels were higher than those in the control group,and serum PCT α1-AG,HPT levels and pulmonary function indicators FEV1,FEV1/FVC increased with the severity of the disease;Serum PCT and HPT were negatively correlated with FEV1 and FEV1/FVC in patients with COPD The level of α1-AG was positively correlated with FEV1%and FEV1/FVC,and the difference was statistically significant(P<0.05).Conclusion Serum PCT The levels of α1-AG and HPT are closely related to the severity of COPD patients,which is of great significance in evaluating the patients'condition.关键词
COPD/降钙素原/α1酸性糖蛋白/触珠蛋白Key words
COPD/Procalcitonin/α Acid glycoprotein/Haptoglobin分类
医药卫生
