基础医学与临床2024，Vol.44Issue(1)：103-107,5.DOI:10.16352/j.issn.1001-6325.2024.01.0103
脂蛋白相关磷脂酶A2在急性冠状动脉综合征中作用的研究进展
Research progress on the role of lipoprotein-associated phospholipase A2 in acute coronary syndrome
摘要
Abstract
Lipoprotein-associated phospholipase A2(Lp-PLA2)is a protein composed of 441 amino acids,which can promote the aggregation of inflammatory cells to the inflammatory response site and the release of inflammatory factors.It can promote the synthesis of matrix metalloproteinases,increase the number of foam cells and extra cel-lular matrix in atherosclerotic plaque,attenuate plaque fiber cap and prone to rupture,thus promote the onset of acute coronary syndrome(ACS).Therefore,the determination and regulation of Lp-PLA2 levels in patients with ACS are clinically significant.关键词
脂蛋白相关磷脂酶A2/急性冠脉综合征/动脉粥样硬化Key words
lipoprotein-associated phospholipase A2/acute coronary syndrome/atherosclerosis分类
医药卫生引用本文复制引用
郭健宏,王亚玲,崔文光..脂蛋白相关磷脂酶A2在急性冠状动脉综合征中作用的研究进展[J].基础医学与临床,2024,44(1):103-107,5.基金项目
张家口市科学技术研究与发展计划(1911021D-1) （1911021D-1）
