国际口腔医学杂志2024，Vol.51Issue(1)：36-44,9.DOI:10.7518/gjkq.2024006
铁死亡在口腔疾病中的研究进展
Ferroptosis and its implication in oral diseases
摘要
Abstract
Ferroptosis is a regulated,iron-dependent form of cell death driven by lipid peroxidation and plays an impor-tant role in a variety of diseases.It has been studied in cancer,ischemia/reperfusion injury diseases,and neurodegenera-tive diseases.As an important form of cell death,ferroptosis has received increasing attention in oral disease research.Some advances have been achieved in related studies.Ferroptosis has become an emerging therapeutic target for oral can-cer and has been associated with many inflammatory injury diseases.As a chronic inflammatory disease,periodontitis may have some correlation with ferroptosis.This work reviews current findings on ferroptosis to provide a reference for the mechanism,diagnosis,and treatment of related oral diseases.关键词
铁死亡/口腔疾病/口腔癌/牙周炎/肿瘤治疗Key words
ferroptosis/oral disease/oral cancer/periodontitis/cancer therapy分类
医药卫生引用本文复制引用
傅豫,何薇,黄兰..铁死亡在口腔疾病中的研究进展[J].国际口腔医学杂志,2024,51(1):36-44,9.基金项目
National Natural Science Foundation of China(82170989) （82170989）
Natural Science Foundation of Chongqing(CSTB2022NSCQ-MSX0794) 国家自然科学基金(82170989) （CSTB2022NSCQ-MSX0794）
重庆市自然科学基金(CSTB2022NSCQ-MSX0794) （CSTB2022NSCQ-MSX0794）
