中国当代医药2023，Vol.30Issue(34)：67-71,5.
儿童多发性大动脉炎10例临床特点分析
Clinical analysis of ten patients with Takayasu arteritis in children
摘要
Abstract
Objective To investigate the clinical features,treatment response and prognosis in patients with Takayasu ar-teritis(TA)in children.Methods Retrospective analysis of clinical data,laboratory examinations,treatment,and prognosis of 10 children with TA in the Department of Renal Rheumatology and Immunology of Children's Hospital Affiliated to Shan-dong University from January 2020 to December 2022.Results There were five boys and five girls in ten patients with Takayasu arteritis.The onset age was from three months to 12 years old.Hypertension was the most common finding on first presentation in 5 cases,followed by vascular accentuated in 3 cases,fever in 6 cases,arthralgia in 2 cases,abdominal pain and vomiting in 3 cases,proteinuria in 2 cases,renal failure in 1 cases.The active indices of inflammation were increased.It showed increased erythrocyte sedimentation rate in 9 case,increased C reactive protein in 7 cases and increased white cell count in 5 cases.Ten patients were treated with steroids and/or immunosuppressant and five patient was treated with biological agent.Two cases were lost to follow-up,and six cases were improved.Conclusion TA in children lacks specific clinical manifestations.For children with recurrent fever,hypertension,high inflammatory reaction and urinary protein positive,the possibility of TA should be considered and angiography should be improved as soon as possible.Glucocorticoid combined with immunosuppressant is effective.关键词
多发性大动脉炎/儿童/临床特点/血管造影Key words
Takayasu arteritis/Children/Clinical featureschild/Angiography分类
医药卫生引用本文复制引用
童桂霞,王兴翠,王雪,仇慧,潘艳艳,张洪霞..儿童多发性大动脉炎10例临床特点分析[J].中国当代医药,2023,30(34):67-71,5.基金项目
山东省济南市卫生健康委科技计划项目(2022-2-151) （2022-2-151）
山东省济南市卫生健康委大数据计划项目(2022-YBD-14). （2022-YBD-14）
