中国当代医药2023，Vol.30Issue(35)：136-139,147,5.
成人社区获得性肺炎564例咽拭子标本非细菌性病原体检测结果分析
Analysis of detection results of non-bacterial pathogens in throat swab specimens of 564 adults with community-acquired pneumonia
摘要
Abstract
Objective The distribution of pathogens in adult community-acquired pneumonia(CAP)was analyzed by throat swab specimens and compared with our previous studies using sputum specimens,so as to provide basis for clinical diagno-sis and treatment.Methods A total of 564 CAP patients in Beijing Chuiyangliu Hospital from October 1,2016 to May 31,2020 were retrospectively selected as the study objects.Throat swab specimens were collected from the patients and the pathogens were detected by polymerase chain reaction(PCR).Results A total of 564 throat swabs were collected from 564 CAP patients,329 of which were not tested for bacteria.The positive rates of bacteria,virus,mycoplasma pneumoniae and chlamydophila pneumoniae were 0,13.3％,21.5％and 0.4％respectively,the detection rate of all throat swab samples was lower than that of the sputum samples used in our earlier stage.The top four non-bacterial pathogens were mycoplasma pneumoniae(121 cases,215％),rhinovirus(18 cases,3.2％),influenza A(14 cases,25％)and parainfluenza virus(11 cases,2.0％).The mycoplasma pneumoniae positive rate was the highest in the 18-＜41 age group(31％),followed by the 41-＜60 age group(16.6％)and the lowest in the ≥60 age group(8.3％).The positive rate of mycoplasma pneumoniae was higher in autumn(26.8％,62/231).Conclusion The major non-bacterial pathogens of CAP in adults are mycoplasma pneumoniae,rhinovirus,in-fluenza A and parainfluenza viruses.The distribution of non-bacterial pathogens of CAP was related to age and season.The detection rate of CAP pathogen in throat swab samples was lower than that in sputum samples.关键词
社区获得性肺炎/成人/细菌/病毒/非典型病原体Key words
Community acquired pneumonia/Adult/Bacteria/Virus/Atypical pathogen分类
医药卫生引用本文复制引用
刘策,孙春荣,姜巧巧,马建新..成人社区获得性肺炎564例咽拭子标本非细菌性病原体检测结果分析[J].中国当代医药,2023,30(35):136-139,147,5.基金项目
"艾滋病和病毒性肝炎等重大传染病防治"科技重大专项项目(2017ZX10103004). （2017ZX10103004）
