广西科学院学报2023，Vol.39Issue(4)：349-362,14.DOI:10.13657/j.cnki.gxkxyxb.20231226.002
红树林来源真菌生物碱类天然产物研究进展
Research Progress of Alkaloids Natural Products from Marine Mangrove Fungi
摘要
Abstract
Marine natural products have always played a very important role in drug development.As a special ecosystem,mangrove contains abundant microbial resources and is a treasure house of high-quality natural re-sources for the discovery of new drug lead compounds.Alkaloids isolated from mangrove fungi are usually novel in structure and have significant bioactivities,which are ideal sources of lead compounds for new drug discovery and have good research and application value.In recent years,the research on alkaloids natural products of mangrove-derived fungi has been developing rapidly.According to the different sources of alka-loids,the alkaloids were classified according to ornithine,lysine,tryptophan,phenylalanine,diketopiperazine and other alkaloids.And 116 novel alkaloids secondary metabolites and their biological activities excavated from mangrove-derived fungi were summarized from 2015 to 2021 in this article.It is intended to provide ref-erence for the study of alkaloids secondary metabolites of mangrove-derived fungi.关键词
红树林/真菌/次级代谢产物/生物碱/生物活性Key words
mangrove/fungi/secondary metabolite/alkaloids/biological activities分类
生物科学引用本文复制引用
杨登峰,黄艳冰,潘丽霞,李红亮,阳丽艳..红树林来源真菌生物碱类天然产物研究进展[J].广西科学院学报,2023,39(4):349-362,14.基金项目
国家自然科学基金项目(31960203),广西科技基地与人才专项(桂科AD23023007)和广西海洋天然产物与组合生物合成化学重点实验室科研业务费项目(GXNNPC2020007)资助. （31960203）
