中国当代医药2023，Vol.30Issue(35)：89-92,4.
2型糖尿病促甲状腺激素与骨代谢的相关性
Correlation between thyroid-stimulating hormone and bone metabolism of type 2 diabetes
摘要
Abstract
Objective To investigate the correlation between thyroid stimulating hormone(TSH)and bone metabolism in type 2 diabetes patients with normal TSH.Methods A total of 239 patients with type 2 diabetes with normal thyroid function in the Department of Endocrinology of Hefei First People's Hospital Lakeside District from January 2016 to November 2021 were retrospectively selected as the study objects,and they were divided into three groups according to the TSH tripartite.The differences of clinical indicators among each group were compared,and the correlation between TSH and each indicator was compared.Results There were significant differences in disease course,age,low density lipoprotein(LDL),procollagen type I N-terminal propeptide(PINP),total cholesterol(TC),beta-isomerized C-telopeptide(β-CTX),free thyroid hor-mones(FT4)and insulin resistance index among three groups(P＜0.05).Spearman correlation analysis showed that TSH was positively correlated with PINP,but TSH was not correlated with calcium,[3-CTX,and OC.Conclusion High TSH in the normal range of type 2 diabetes can increase bone formation index and active bone formation,which is expected to reduce the occurrence of osteoporosis.关键词
糖尿病/促甲状腺激素/骨代谢/相关性Key words
Diabetes/Thyroid stimulating hormone/Bone metabolism/Correlation分类
医药卫生引用本文复制引用
江旭,王国娟,陈丽,朱彰祥,叶启宝..2型糖尿病促甲状腺激素与骨代谢的相关性[J].中国当代医药,2023,30(35):89-92,4.基金项目
安徽省合肥市应用医学研究项目. （）
